NIPT

NIPT

NIPT

  • It is an advanced screening test for detection of chromosomal abnormalities in fetus.

  • It is a blood test that looks at small fragment s of DNA from the developing fetus through maternal blood.

  • By looking at these fetal DNA fragments, NIPT can tell you about the chance of your pregnancy having chromosomal aneuplodies.

  • NIPT looks for : The three most common chromosomal conditions seen in pregnancy (1) Down syndrome (Chromosome 21) (2) Edwards syndrome (Chromosome 18) (3) Patau syndrome(Chromosome 13)

  • Accuracy is 97 to 99 % (NOT 100%).

  • The high risk cases are always recommended for invasive test for the confirmation.

  • NIPT is not a diagnostic test.
  • It does not screen for structural defects.
  • Does not screen for every chromosomal or genetic condition.
  • The cost of the test is 9.5k.
  • Not suitable for triplet and higher multiple pregnancies.

  • You can have NIPT anytime from 10 weeks of pregnancy.

  • Having NIPT or any other type of genetic prenatal screening test is completely VOLUNTARY.

  • Turn around time for results is usually within 7-10days.

  • SCREENING TESTS
    1. Used to suspect diseases early.
    2. For all pregnant women
    3. Double marker test, NIPT, quadruple marker test, etc are screening tests
  • DIAGNOSTIC TESTS
    1. Used to establish the presence or absence of disease.
    2. For individuals with a positive screening test.
    3. Chorionic Villus Sample (CVS), Amniocentesis, etc. are diagnostic test

NIPT

NIPT

  • Low risk

    1. This means it is very unlikely that your pregnancy has any of the specific conditions screened. But other conditions may still be present.

  • High risk

    1. A high risk result means there is an increased chance of the chromosome condition in your pregnancy.
    2. You should have a diagnostic test to confirm the result.

  • No result

    1. In some cases no result is obtained. This is very uncommon. It is sometimes caused when there aren’t enough DNA pieces of fetus in your blood.

  • For a low risk NIPT result:

    1. Routine follow up.

  • For a high risk NIPT result:

    1. Refer for genetic counselling .
    2. Always offer invasive testing for confirmation.
    3. Patients should never be offered the option of termination without confirmation.

Yes, Guidelines suggest all patients should have 18-20 weeks anomaly ultra- sonography to check (your) baby’s development & physical anomaly.

NIPT

NIPT

Basic difference between NIPT & Double Marker

Basic difference between NIPT & Double Marker

This information aims to helps you make the best decision regarding your care. It is not meant to replace advice from a doctor about your own situation.